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Intrahepatic Cholestasis (Type I, II, III)

Cholestasis is reduced or stopped bile flow. "Chole" refers to bile and "stasis" means keeping at the same level. Bile flow may be blocked inside the liver (intrahepatic), outside the liver (extrahepatic) or in both places.

Causes of Cholestasis

  • Hepatitis
  • Metabolic liver diseases
  • Drug effects
  • A stone in the bile duct
  • Bile duct narrowing
  • Biliary atresia
  • Inflammation of the pancreas

Symptoms of Cholestasis

  • Jaundice
  • Dark urine
  • Pale stool
  • Bone loss
  • Easy bleeding
  • Itching
  • Small, spider-like blood vessels visible in the skin
  • Enlarged spleen
  • Fluid in the abdominal cavity
  • Chills
  • Pain from the biliary tract or pancreas
  • Enlarged gallbladder