Primary Biliary Cirrhosis

Primary biliary cirrhosis is an inflammatory condition of bile ducts resulting in narrowing and obstruction of the flow of bile, causing damage to the liver cells. The onset of symptoms is gradual, most commonly with fatigue and itching skin as the first symptom. Long-standing bile obstruction is believed to lead to liver cirrhosis. The disease may be associated with autoimmune disorders.

How This Hurts the Liver

Bile ducts within the liver become inflamed due to an unknown cause.


Therapy is aimed at treating the symptoms and prevention of complications.