Innovative Therapy for Patients with Pediatric Cancers

Helping to Provide Every Chance for a Cure

innovative therapy patientFIND A CLINICAL TRIAL

During the last several decades, many drugs identified as beneficial in innovative therapy trials have been moved into front-line treatment for patients with various pediatric cancers. 

For many young patients with cancer and blood disorders, innovative therapy represents hope.

What is Innovative Therapy?

Innovative therapy focuses on the development of new treatments for patients with cancer or blood disorders. 

Most commonly, innovative therapy attempts to identify new drugs that can benefit patients with:

  • Tumors that have failed to respond to standard treatment
  • Tumors that have returned

Innovative therapy trials also attempt to identify drugs that are:

  • Safer to administer
  • Less toxic to patients and cause fewer short-term and long-term side effects
  • Easier to give to patients (e.g., replacing an I.V. drug with the same drug that can be given by mouth)
  • More effective when given in combination compared to when given as a single drug

We hope that the new combination or new ways of administering the medicine will lead to a better outcome in treating the disease.

Physician Leaders

Cynthia Wetmore, M.D., Ph.D.Cynthia Wetmore, M.D., Ph.D. 
Director, Innovative Therapy/Phase I Program
Assistant Professor of Pediatrics
Research interests:
Actively involved in bringing new, targeted agents to Phase I/II clinical trials for the treatment of children with brain tumors

Tobey J. MacDonald, M.D. 
Director, Pediatric Neuro-oncology Program
Associate Professor of Pediatrics
Research interests:
Basic and translational research of childhood brain tumors with primary research focus on the role of platelet-derived growth factor receptor (PDGFR) signaling in medulloblastoma

Who We Treat

The Aflac Cancer Center also treats adolescents and young adults (age 15 to 21), who can benefit from the pediatric protocols and access to clinical trials.

Due to their age, adolescents and young adults are often treated at adult hospitals where they don’t have access to pediatric clinical trials. But, many adolescents and young adults have better results when they are on pediatric clinical trials instead of adult clinical trials. 


Physicians and researchers at the Aflac Cancer Center are faculty members at Emory University School of Medicine.

Some physicians and affiliated healthcare professionals who perform services at Children's Healthcare of Atlanta are independent providers and are not our employees.